The FUT 21 TOTW 6 could include three of London's biggest talents - Hakim Ziyech, Gareth Bale and Thomas Partey.
Ziyech starred in Chelsea 's comfortable 3-0 win at Burnley, scoring his first Premier League goal, as well as providing an assist to Timo Werner to wrap up the game for the Blues.
Bale scored his first goal since re-joining Tottenham and that proved to be the decisive goal in a 2-1 win over Brighton & Hove Albion in North London.
Meanwhile, Partey produced a fantastic performance for Arsenal as they ran out eventual 1-0 winners over Manchester United at Old Trafford.
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Check out the Arsenal, Chelsea and Tottenham Hotspur players in line for a possible in-form in TOTW 6 this week.
Hakim Ziyech
The Moroccan attacker is finding his feet with his new club after a disrupted start due to an injury problem.
Ziyech scored in last week's 4-0 win over Krasnodar in the Champions League, and carried on his great start with a goal and an assist for Frank Lampard 's side at Turf Moor.
The 27-year-old has a OTW (One To Watch) card, that is currently rated at the same (85) as his base Gold card.
Following his brilliant display against Burnley, the former Ajax star is set to see his OTW item's rating increase.
Kurt Zouma
The Chelsea centre-back could be included in the latest FUT 21 TOTW squad after scoring the Blues' second, as well as keeping a clean sheet.
Zouma headed in from a Mason Mount corner to put the visitors 2-0 up in Lancashire, and was in fine form at the back for Lampard's side.
Usually, only one player from a team gets picked for TOTW, unless it's extraordinary circumstances, so the French defender could miss out due to his team-mate Ziyech's exploits.
Gareth Bale
Bale scored his first goal (for a second time) for Spurs, as they narrowly beat Brighton at home.
Sergio Reguilon - another of Jose Mourinho 's new signings - produced a fantastic delivery, which the Welshman headed past Robert Sanchez.
Bale, like Ziyech, has a OTW card which is currently rated 83 and it could easily go up after the 31-year-old's winning goal.
If Bale does get an IF card, then it's likely to be a RW, after coming on for Erik Lamela on 70 minutes.
Thomas Partey
Partey was one of - it not, the - standout player for the Gunners in their impressive 1-0 victory over Manchester United.
The Ghana midfielder was brought into the Emirates Stadium to try and add some much-needed solidity in the centre of the field, and he showed that in abundance at Old Trafford.
Even the most brutal of pundits, Roy Keane, was taken aback by Partey's display for Arsenal, when talking on Sky Sports: "He was outstanding. He's obviously no mug having played in big games.
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"When you watch a player live that's when you can judge a player and the more I look at him, the more I wish he was in the United midfield."
The 27-year-old has a OTW card, that is rated at 86 already following a fine performance for Ghana that saw the Gunners star pick up a +2 upgrade.
Gabriel Magalhaes
It was perhaps Gabriel 's best performance for his new club since signing from Lille in the summer.
The Brazilian defender was a rock for the travelling Gunners and was praised massively by the Sky Sports pundits.
Gary Neville, who was on co-commentary for the match, called Gabriel the best player on the pitch.
Neville said: "Gabriel has been fantastic, so far I’d say he’s been the best player on the pitch, for me."
Hector Bellerin
Bellerin was in fine form for Mikel Arteta's side and is also in contention to be named in the latest TOTW.
The Arsenal right-back won the penalty for the Gunners, after Paul Pogba brought him down in the box.
Pierre-Emerick Aubameyang scored from 12 yards to hand Arteta's side the three points in Manchester - helped by the fantastic work of Bellerin.
The Spaniard was also part of a back-line that kept a crucial clean sheet at Old Trafford, but like the aforementioned Zouma, he could miss out due to one of his team-mate's performance.
Check out the full TOTW 6 predictions below.
FIFA 21 Ultimate Team TOTW (Team of the Week) 6 predictions
GK: Andrea Consigli (Sassuolo)
CB: Matts Hummels (Borussia Dortmund)
CB: Gabriel Magalhaes (Arsenal)
RB: Kyle Walker (Manchester City)
LM: Jack Grealish (Aston Villa)
CM: Sergio Canales (Real Betis)
CAM: Hakim Ziyech (Chelsea)
RW: Gareth Bale (Tottenham)
CF: Joao Felix (Atletico Madrid)
CF: Karim Benzema (Real Madrid)
ST: Cristiano Ronaldo (Piemonte Calcio/Juventus)
FIFA 21 is out now on Xbox One, PlayStation 4 and PC. The next-generation version of the game set to be released on December 4, for PlayStation 5, Xbox Series X and Xbox Series S.
Fans who jump into FIFA 21 can also benefit from Dual Entitlement, enabling them to upgrade their copy of the game from PlayStation 4 to PlayStation 5, or Xbox One to Xbox Series X/S at no extra cost.
All progress made or content acquired within FIFA 21 Ultimate Team (including players, items, coins, FIFA Points, match record, and leaderboard placement), as well as all progression in VOLTA FOOTBALL, will transfer over to PlayStation 5 or Xbox Series.